Manufacture News and New Product Update

Pyrimidine, 4-bromo-2-chloro- (9CI) CAS 885702-34-1, Purity 98%,white powder
Uses:Used as an primary and secondary intermediate for pharmaceutical, organic synthesis

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N-BOC-ALPHA-METHYL-L-PROLINE CAS 103336-06-7(98%, ee 99%, white powder)
Synonyms: N-BOC-A-METHYL-L-PROLINE;1-(tert-butoxycarbonyl)-2-methyl-L-proline(SALTDATA: FREE);1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2S)-;N-Boc-2-Methyl-L-proline, 97%;N-BOC-ALPHA-METHYL-L-PROLINE;1-Boc-2-Methyl-L-proline;(S)-1-Boc-2-Methyl-proline;(S)-N-BOC-Α-METHYLPROLINE
Uses N-Boc-2-methyl-L-proline is used as pharmaceutical intermediate. Raw materials (S)-2-Methyl-2-pyrrolidinecarboxylicacid-->1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)--->(S)-2-Methylproline-->L-Proline-->Di-tert-butyl dicarbonate-->2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

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7-Carboxy-1H-indazole CAS 677304-69-7 (purity 99%min, packing 25kg/drum)
Synonyms: 7-INDAZOLE CARBOXYLLIC ACID;1H-INDAZOLE-7-CARBOXYLIC ACID;7-INDAZOLE CARBOXYLIC ACID;7-Carboxy-1H-indazole;7-(1H)Indazole carboxylic acid;1H-Indazol-7-carboxylic acid;Niraparib Intermediate4;
Uses: 1H-indazole-7-carboxylic Acid is an inhibitor of nitric oxide synthases.

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Tryptophol CAS 526-55-6 (purity 99%min, packing: 25kg/drum).
Chemical Properties:3-(2-Hydroxyethyl)indole [526-55-6], tryptophol, C10H11NO, Mr 161.20, mp 59 ℃, bp 174 ℃, (2 kPa) forms colorless prisms or flakes that are readily soluble in methanol, ethanol, diethyl ether, chloroform, and acetone, soluble in benzene, and slightly soluble in water. It is produced by reacting methyl-1H-indole-3-acetate with lithium aluminum hydride, or through reduction of methyl-1H-indole-3-glyoxylate with sodium borohydride. The antihypertensive Indoramin is produced from tryptophol.
Uses:Reactant for preparation of:Inhibitors of the C-terminal domain of RNA polymerase II and their antitumor activities; Anti-HIV-1 agents;Inhibitors of Protein-Protein Interactions; Partial agonists of the; serotonin 5-HT1A receptor; Growth hormone secretagogues; Vascular endothelial growth factor (VEGF) inhibitors; A2B adenosine receptor ligands;Potential detoxification inhibitors of the crucifer phytoalexin brassinin; Inhibitors of interleukine 6; Dual binding site acetylcholinesterase inhibitors

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17th edition of CPHI & PMEC India expo
The 17th edition of CPHI & PMEC India, organised by Informa Markets in India, returns in an advanced format, scheduled from November 26-28, 2024, at the India Expo Centre, Greater Noida, Delhi-NCR. Renowned as a comprehensive, one-stop destination for innovative, cost-effective solutions, the expo will be showcasing the pharmaceutical industry’s modernisation, innovation, and sustainability.

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4-[(4-CHLORO-2-PYRIMIDINYL)AMINO]BENZONITRILE CAS: 244768-32-9 (purity 98%min, packing 25kg/drum)
Synonyms: 4-N[2(4-CHLOROPYRIMIDINYL)]-AMINO BENZONITRILE;4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile;Benzonitrile, 4-[(4-chloro-2-pyriMidinyl)aMino]-;4-((4-Chloropyrimidin-2-yl);Rilpivirine Chloro Impurity;4-[(4-CHLORO-2-PYRIMIDINYL)AMINO]BENZONITRILE ISO 9001：2015 REACH;4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrileQ: What is 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile Q: What is the CAS Number of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile Q: What is the storage condition of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile Q: What are the applications of 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile
Uses: 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile is used in the preparation of 2-naphthyl substituted diarylpyrimidines (DAPY) analogues. and synthesis of Rilpivirine

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METHYL 6-AMINONICOTINATE CAS: 36052-24-1 (yellow powder, purity 98%, 25kg/drum, new manufacture project)
Synonyms:METHYL 2-AMINO-5-PYRIDINECARBOXYLATE;METHYL 2-AMINOPYRIDINE-5-CARBOXYLATE;6-AMINONICOTINIC ACID METHYL ESTER;6-Aminonicotinic;Methyl 6-aminonicotinate 98%;3-Pyridinecarboxylic acid, 6-amino-, methyl ester;6-Aminonicotinic Acid Methyl Ether
Product Categories: Heterocyclic Building Blocks;Heterocycles;Amines;blocks;pharmacetical;Esters;Carboxes;Pyridines;1H-Inden-1-ol
USE: Methyl 6-aminonicotinate can be used in ointments for treatment of psoriasis.

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1-METHYL-5-NITROIMIDAZOLE CAS 3034-42-2 (purity:99%, pale yellow crystal, 25kg/drum)
Synonyms: 1H-Imidazole, 1-methyl-5-nitro-;1-methyl-5-nitro-imidazol;Imidazole, 1-methyl-5-nitro-;1-Methyl-5-nitroimidazole >97.0% (HPLC);Metronidazole Impurity 4;1-METHYL-5-NITROIMIDAZOLE
Uses: 1-Methyl-5-nitroimidazole is used in the synthesis of new 5-nitroimidazoles as potential antibacterial drugs via VNS procedure.

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2,5-Dibromopyrazine CAS 23229-26-7 (purity: 99%, 1kg/bottle,new RD project)
Synonyms: 2,5-DIBROMOPYRAZINE;3,6-Dibromopyrazine, 2,5-Dibromo-1,4-diazine;2,5-Dibromopyrazine (GC);2,5-bisbromopyrazine;PYRAZINE,2,5-DIBROMO;2,5-Dibromopyrazine>;2,5-Dibromopyrazine 2015 REACH;5-Dibromopyrazine
Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Pyrazine
Sacle: kg to hundred KG

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2-Cyclohexylmandelic acid CAS 4335-77-7 (Purity 98%, off-white powder, 25kg/drum)
Synonyms: acidephenylcyclohexylhydroxyacetique;alpha-cyclohexyl-alpha-hydroxy-benzeneaceticaci;alpha-cyclohexyl-alpha-hydroxybenzeneaceticacid;alpha-phenyl-cyclohexaneglycolicaci;alpha-phenylcyclohexaneglycolicacid;ALPHA CYCLOHEXYL MANDELIC ACID;Benzeneacetic acid,α-cyclohexyl-α-hydroxy-;α-Cyclohexylmandelic acid
Uses intermediate for Oxybutynin HCl, Oxyphenonium Bromide; An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.

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